Drug interactions
Cidofovir + Hydroxycarbamide
Severity: Moderate
Cidofovir and Hydroxycarbamide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can suppress bone marrow function, and cidofovir can cause neutropenia. Used together they may produce deeper or more prolonged cytopenias than either drug alone.
What this interaction means in plain words
Cidofovir and Hydroxycarbamide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cidofovir belongs to Anti Virals; Hydroxycarbamide belongs to Oncology.
Why it happens
Additive myelosuppressive effects (pharmacodynamic).
What to do
Monitor complete blood counts with differential regularly during combined therapy. Reduce the dose or interrupt one agent if significant neutropenia or thrombocytopenia develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Cidofovir
- Amikacin + Cidofovir Contraindicated
- Amphotericin b deoxycholate + Cidofovir Contraindicated
- Amphotericin b + Cidofovir Contraindicated
- Bacitracin + Cidofovir Contraindicated
- Capreomycin + Cidofovir Contraindicated
- Cephaloridine + Cidofovir Contraindicated
Other interactions of Hydroxycarbamide
- Didanosine + Hydroxycarbamide Contraindicated
- Hydroxycarbamide + Stavudine Contraindicated
- Adenovirus types 4 and 7 live + Hydroxycarbamide Major
- Axicabtagene ciloleucel + Hydroxycarbamide Major
- Bcg intravesical live + Hydroxycarbamide Major
- Bcg vaccine live + Hydroxycarbamide Major
Frequently asked questions
Can I take Cidofovir with Hydroxycarbamide?
MediHelp rates the interaction as moderate. Cidofovir and Hydroxycarbamide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can suppress bone marrow function, and cidofovir can cause neutropenia. Used together they may produce deeper or more prolonged cytopenias than either drug alone.
How serious is the interaction between Cidofovir and Hydroxycarbamide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor complete blood counts with differential regularly during combined therapy. Reduce the dose or interrupt one agent if significant neutropenia or thrombocytopenia develops.
What other medicines interact with Cidofovir?
MediHelp also lists interactions of Cidofovir with, for example, Amikacin, Amphotericin b deoxycholate, Amphotericin b. The full list is on the Cidofovir page.
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