Drug interactions
Ciprofloxacin + Elagolix
Severity: Minor
Ciprofloxacin and Elagolix: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Elagolix inhibits P-glycoprotein and could modestly raise levels of P-gp substrates such as ciprofloxacin. A clinically important increase is not expected.
What this interaction means in plain words
Ciprofloxacin and Elagolix have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ciprofloxacin belongs to Anti Bacterial; Elagolix belongs to Musculoskeletal.
Why it happens
Elagolix inhibition of P-glycoprotein efflux may increase ciprofloxacin absorption.
What to do
No dose change is generally needed. Be aware of increased ciprofloxacin adverse effects if symptoms appear.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ciprofloxacin
- Agomelatine + Ciprofloxacin Contraindicated
- Ciprofloxacin + Fezolinetant Contraindicated
- Ciprofloxacin + Thioridazine Contraindicated
- Ciprofloxacin + Tizanidine Contraindicated
- Ciprofloxacin + Vandetanib Contraindicated
- Alosetron + Ciprofloxacin Major
Other interactions of Elagolix
- Cyclosporin + Elagolix Contraindicated
- Elagolix + Gemfibrozil Contraindicated
- Desogestrel-ethinyl estradiol + Elagolix Major
- Elagolix + Erythromycin Major
- Elagolix + Ethinyl estradiol-drospirenone Major
- Elagolix + Ethinyl estradiol-levonorgestrel Major
Frequently asked questions
Can I take Ciprofloxacin with Elagolix?
MediHelp rates the interaction as minor. Ciprofloxacin and Elagolix have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Elagolix inhibits P-glycoprotein and could modestly raise levels of P-gp substrates such as ciprofloxacin. A clinically important increase is not expected.
How serious is the interaction between Ciprofloxacin and Elagolix?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is generally needed. Be aware of increased ciprofloxacin adverse effects if symptoms appear.
What other medicines interact with Ciprofloxacin?
MediHelp also lists interactions of Ciprofloxacin with, for example, Agomelatine, Fezolinetant, Thioridazine. The full list is on the Ciprofloxacin page.
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