Drug interactions
Cisatracurium + Prochlorperazine
Severity: Minor
Cisatracurium and Prochlorperazine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cisatracurium is a neuromuscular blocker given intravenously in anesthesia or intensive care, with no meaningful oral interaction. Phenothiazines have been reported to have minor effects on neuromuscular blockade, but a clear, clinically important interaction is not established.
What this interaction means in plain words
Cisatracurium and Prochlorperazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cisatracurium belongs to Musculoskeletal; Prochlorperazine belongs to Central Nervous System.
Why it happens
No well-established mechanism; phenothiazines may weakly potentiate neuromuscular blockade.
What to do
No dose change is needed; monitor neuromuscular function with a nerve stimulator as is standard during blockade.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Prochlorperazine
- Dronedarone + Prochlorperazine Contraindicated
- Ibutilide + Prochlorperazine Contraindicated
- Nilotinib + Prochlorperazine Contraindicated
- Pimozide + Prochlorperazine Contraindicated
- Prochlorperazine + Thioridazine Contraindicated
- Amiodarone + Prochlorperazine Major
Other interactions of Cisatracurium
Frequently asked questions
Can I take Cisatracurium with Prochlorperazine?
MediHelp rates the interaction as minor. Cisatracurium and Prochlorperazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cisatracurium is a neuromuscular blocker given intravenously in anesthesia or intensive care, with no meaningful oral interaction. Phenothiazines have been reported to have minor effects on neuromuscular blockade, but a clear, clinically important interaction is not established.
How serious is the interaction between Cisatracurium and Prochlorperazine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is needed; monitor neuromuscular function with a nerve stimulator as is standard during blockade.
What other medicines interact with Prochlorperazine?
MediHelp also lists interactions of Prochlorperazine with, for example, Dronedarone, Ibutilide, Nilotinib. The full list is on the Prochlorperazine page.
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