Drug interactions
Cisplatin + Nitazoxanide
Severity: Minor
Cisplatin and Nitazoxanide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nitazoxanide's active metabolite is highly protein bound and could theoretically displace other highly bound drugs. Cisplatin binds plasma proteins avidly, but no clinically meaningful interaction has been demonstrated.
What this interaction means in plain words
Cisplatin and Nitazoxanide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cisplatin belongs to Oncology; Nitazoxanide belongs to Anti Bacterial.
Why it happens
Theoretical competition for plasma protein binding sites.
What to do
No specific action beyond routine monitoring of cisplatin toxicity is needed. Check for unexpected adverse effects if nitazoxanide is given during cisplatin treatment.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cisplatin
- Cidofovir + Cisplatin Contraindicated
- Adefovir + Cisplatin Major
- Adenovirus types 4 and 7 live + Cisplatin Major
- Amikacin + Cisplatin Major
- Amphotericin b deoxycholate + Cisplatin Major
- Amphotericin b + Cisplatin Major
Other interactions of Nitazoxanide
Frequently asked questions
Can I take Cisplatin with Nitazoxanide?
MediHelp rates the interaction as minor. Cisplatin and Nitazoxanide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Nitazoxanide's active metabolite is highly protein bound and could theoretically displace other highly bound drugs. Cisplatin binds plasma proteins avidly, but no clinically meaningful interaction has been demonstrated.
How serious is the interaction between Cisplatin and Nitazoxanide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action beyond routine monitoring of cisplatin toxicity is needed. Check for unexpected adverse effects if nitazoxanide is given during cisplatin treatment.
What other medicines interact with Cisplatin?
MediHelp also lists interactions of Cisplatin with, for example, Cidofovir, Adefovir, Adenovirus types 4 and 7 live. The full list is on the Cisplatin page.
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