Drug interactions
Dasatinib + Goserelin
Severity: Moderate
Dasatinib and Goserelin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dasatinib can prolong the QT interval, and androgen deprivation with goserelin may contribute. The combination may slightly raise arrhythmia risk, particularly in patients with cardiac disease or low electrolytes.
What this interaction means in plain words
Dasatinib and Goserelin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dasatinib belongs to Oncology; Goserelin belongs to Endocrine.
Why it happens
Additive QT prolongation from dasatinib and goserelin-induced androgen deprivation.
What to do
Check an ECG at baseline and during treatment, and correct hypokalemia and hypomagnesemia. Avoid adding other QT-prolonging drugs where possible.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Goserelin
Other interactions of Dasatinib
- Dasatinib + Saquinavir Contraindicated
- Dasatinib + Thioridazine Contraindicated
- Adagrasib + Dasatinib Major
- Amiodarone + Dasatinib Major
- Amisulpride + Dasatinib Major
- Amitriptyline + Dasatinib Major
Frequently asked questions
Can I take Dasatinib with Goserelin?
MediHelp rates the interaction as moderate. Dasatinib and Goserelin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dasatinib can prolong the QT interval, and androgen deprivation with goserelin may contribute. The combination may slightly raise arrhythmia risk, particularly in patients with cardiac disease or low electrolytes.
How serious is the interaction between Dasatinib and Goserelin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check an ECG at baseline and during treatment, and correct hypokalemia and hypomagnesemia. Avoid adding other QT-prolonging drugs where possible.
What other medicines interact with Goserelin?
MediHelp also lists interactions of Goserelin with, for example, Amisulpride, Arsenic trioxide, Artemether / lumefantrine. The full list is on the Goserelin page.
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