Drug interactions
Dasatinib + Indacaterol
Severity: Moderate
Dasatinib and Indacaterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both agents can prolong the QT interval, and long-acting beta-2 agonists may also provoke tachycardia and hypokalemia. Together they may increase the risk of ventricular arrhythmias, particularly in patients with other risk factors.
What this interaction means in plain words
Dasatinib and Indacaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dasatinib belongs to Oncology; Indacaterol belongs to Respiratory.
Why it happens
Additive QT prolongation through pharmacodynamic effects, with beta-2 agonist related hypokalemia as a possible contributor.
What to do
Obtain a baseline ECG and correct potassium and magnesium before starting the combination. Repeat the ECG and monitor electrolytes if other QT-prolonging drugs are present or symptoms occur.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol
Other interactions of Dasatinib
- Dasatinib + Saquinavir Contraindicated
- Dasatinib + Thioridazine Contraindicated
- Adagrasib + Dasatinib Major
- Amiodarone + Dasatinib Major
- Amisulpride + Dasatinib Major
- Amitriptyline + Dasatinib Major
Frequently asked questions
Can I take Dasatinib with Indacaterol?
MediHelp rates the interaction as moderate. Dasatinib and Indacaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both agents can prolong the QT interval, and long-acting beta-2 agonists may also provoke tachycardia and hypokalemia. Together they may increase the risk of ventricular arrhythmias, particularly in patients with other risk factors.
How serious is the interaction between Dasatinib and Indacaterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG and correct potassium and magnesium before starting the combination. Repeat the ECG and monitor electrolytes if other QT-prolonging drugs are present or symptoms occur.
What other medicines interact with Indacaterol?
MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.
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