Drug interactions
Desflurane + Goserelin
Severity: Moderate
Desflurane and Goserelin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Goserelin, as an androgen deprivation therapy, may prolong the QT interval, and desflurane can also affect repolarization. The combined effect is likely small but relevant in patients with other risk factors.
What this interaction means in plain words
Desflurane and Goserelin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Desflurane belongs to Central Nervous System; Goserelin belongs to Endocrine.
Why it happens
Additive QT prolongation, with androgen deprivation affecting cardiac repolarization.
What to do
Review baseline ECG and electrolytes in patients with other QT risk factors. Monitor the ECG during anesthesia.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Desflurane and Goserelin, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Desflurane
Other interactions of Goserelin
Frequently asked questions
Can I take Desflurane with Goserelin?
MediHelp rates the interaction as moderate. Desflurane and Goserelin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Goserelin, as an androgen deprivation therapy, may prolong the QT interval, and desflurane can also affect repolarization. The combined effect is likely small but relevant in patients with other risk factors.
How serious is the interaction between Desflurane and Goserelin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Review baseline ECG and electrolytes in patients with other QT risk factors. Monitor the ECG during anesthesia.
What other medicines interact with Desflurane?
MediHelp also lists interactions of Desflurane with, for example, Amisulpride, Anagrelide, Arsenic trioxide. The full list is on the Desflurane page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
