Drug interactions
Desflurane + Triclabendazole
Severity: Moderate
Desflurane and Triclabendazole: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Triclabendazole can prolong the QT interval, and volatile anesthetics have a similar effect. Combining them may increase the risk of ventricular arrhythmia, especially in patients with other risk factors.
What this interaction means in plain words
Desflurane and Triclabendazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Desflurane belongs to Central Nervous System; Triclabendazole belongs to Anti Parasitic.
Why it happens
Additive QTc prolongation.
What to do
Check a baseline ECG and electrolytes if anesthesia is needed during treatment, and ideally defer elective procedures until the course has finished. Monitor the ECG intraoperatively.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Desflurane
Other interactions of Triclabendazole
Frequently asked questions
Can I take Desflurane with Triclabendazole?
MediHelp rates the interaction as moderate. Desflurane and Triclabendazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Triclabendazole can prolong the QT interval, and volatile anesthetics have a similar effect. Combining them may increase the risk of ventricular arrhythmia, especially in patients with other risk factors.
How serious is the interaction between Desflurane and Triclabendazole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check a baseline ECG and electrolytes if anesthesia is needed during treatment, and ideally defer elective procedures until the course has finished. Monitor the ECG intraoperatively.
What other medicines interact with Desflurane?
MediHelp also lists interactions of Desflurane with, for example, Amisulpride, Anagrelide, Arsenic trioxide. The full list is on the Desflurane page.
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