Drug interactions
Digoxin + Imidapril
Severity: Minor
Digoxin and Imidapril: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
ACE inhibitors have been associated with small increases in digoxin levels in some studies, but the data for imidapril are limited. ACE inhibitors may also affect renal function and potassium, which can influence digoxin toxicity.
What this interaction means in plain words
Digoxin and Imidapril have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Digoxin belongs to Cardiovascular; Imidapril belongs to Cardiovascular.
Why it happens
Mechanism not established; possible reduction in renal digoxin clearance and effects on renal function and potassium.
What to do
Monitor renal function, potassium and digoxin levels when starting imidapril.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Digoxin and Imidapril, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Digoxin
- Digoxin + Lily of the valley Contraindicated
- Digoxin + Squill Contraindicated
- Adagrasib + Digoxin Major
- Amiodarone + Digoxin Major
- Amlodipine-hydrochlorothiazide-valsartan + Digoxin Major
- Amphotericin b deoxycholate + Digoxin Major
Other interactions of Imidapril
- Amiloride + Imidapril Major
- Eplerenone + Imidapril Major
- Imidapril + Lithium Major
- Imidapril + Pregabalin Major
- Imidapril + Spironolactone Major
- Imidapril + Triamterene Major
Frequently asked questions
Can I take Digoxin with Imidapril?
MediHelp rates the interaction as minor. Digoxin and Imidapril have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. ACE inhibitors have been associated with small increases in digoxin levels in some studies, but the data for imidapril are limited. ACE inhibitors may also affect renal function and potassium, which can influence digoxin toxicity.
How serious is the interaction between Digoxin and Imidapril?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function, potassium and digoxin levels when starting imidapril.
What other medicines interact with Digoxin?
MediHelp also lists interactions of Digoxin with, for example, Lily of the valley, Squill, Adagrasib. The full list is on the Digoxin page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
