Drug interactions
Disopyramide + Dulaglutide
Severity: Minor
Disopyramide and Dulaglutide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dulaglutide slows gastric emptying and might change the absorption timing of oral disopyramide, which has a narrow therapeutic index. Significant effects have not been established.
What this interaction means in plain words
Disopyramide and Dulaglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Disopyramide belongs to Cardiovascular; Dulaglutide belongs to Endocrine.
Why it happens
Delayed gastric emptying may alter the rate of oral absorption.
What to do
Monitor ECG and clinical response to disopyramide when dulaglutide is started or titrated. Check serum levels if toxicity or loss of effect is suspected.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dulaglutide
Other interactions of Disopyramide
- Amisulpride + Disopyramide Contraindicated
- Desipramine + Disopyramide Contraindicated
- Disopyramide + Dronedarone Contraindicated
- Disopyramide + Itraconazole Contraindicated
- Disopyramide + Ketoconazole Contraindicated
- Disopyramide + Maprotiline Contraindicated
Frequently asked questions
Can I take Disopyramide with Dulaglutide?
MediHelp rates the interaction as minor. Disopyramide and Dulaglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dulaglutide slows gastric emptying and might change the absorption timing of oral disopyramide, which has a narrow therapeutic index. Significant effects have not been established.
How serious is the interaction between Disopyramide and Dulaglutide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and clinical response to disopyramide when dulaglutide is started or titrated. Check serum levels if toxicity or loss of effect is suspected.
What other medicines interact with Dulaglutide?
MediHelp also lists interactions of Dulaglutide with, for example, Insulin degludec-liraglutide, Insulin glargine-lixisenatide, Alogliptin-metformin. The full list is on the Dulaglutide page.
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