Drug interactions
Dopamine + Indacaterol-glycopyrronium
Severity: Moderate
Dopamine and Indacaterol-glycopyrronium: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dopamine has dose-dependent adrenergic activity, and combining it with indacaterol may potentiate cardiovascular beta-adrenergic effects. Tachycardia, arrhythmias, hypertension and hypokalemia may occur. The risk is greatest at higher dopamine doses and in patients with cardiac disease.
What this interaction means in plain words
Dopamine and Indacaterol-glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dopamine belongs to Cardiovascular; Indacaterol-glycopyrronium belongs to Respiratory.
Why it happens
Additive adrenergic receptor stimulation.
What to do
Monitor ECG, blood pressure and serum potassium during dopamine infusion. Use the lowest effective dopamine dose.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol-glycopyrronium
Other interactions of Dopamine
- Dihydroergotamine intranasal + Dopamine Contraindicated
- Dihydroergotamine + Dopamine Contraindicated
- Dopamine + Promethazine Contraindicated
- Dopamine + Selegiline transdermal Contraindicated
- Amitriptyline + Dopamine Major
- Clomipramine + Dopamine Major
Frequently asked questions
Can I take Dopamine with Indacaterol-glycopyrronium?
MediHelp rates the interaction as moderate. Dopamine and Indacaterol-glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dopamine has dose-dependent adrenergic activity, and combining it with indacaterol may potentiate cardiovascular beta-adrenergic effects. Tachycardia, arrhythmias, hypertension and hypokalemia may occur. The risk is greatest at higher dopamine doses and in patients with cardiac disease.
How serious is the interaction between Dopamine and Indacaterol-glycopyrronium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG, blood pressure and serum potassium during dopamine infusion. Use the lowest effective dopamine dose.
What other medicines interact with Indacaterol-glycopyrronium?
MediHelp also lists interactions of Indacaterol-glycopyrronium with, for example, Amisulpride, Arformoterol, Arsenic trioxide. The full list is on the Indacaterol-glycopyrronium page.
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