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Drug interactions

Dutasteride-tamsulosin + Elagolix

Severity: Minor

Dutasteride-tamsulosin and Elagolix: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Elagolix is a weak to moderate CYP3A4 inducer and may modestly reduce tamsulosin and dutasteride exposure. The clinical consequence is likely small.

What this interaction means in plain words

Dutasteride-tamsulosin and Elagolix have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Dutasteride-tamsulosin belongs to Genitourinary; Elagolix belongs to Musculoskeletal.

Evidence level: Low

Why it happens

CYP3A4 induction by elagolix increases metabolism of tamsulosin and dutasteride.

What to do

Monitor urinary symptom control. Raise the dose only if efficacy is clearly reduced.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Dutasteride-tamsulosin with Elagolix?

MediHelp rates the interaction as minor. Dutasteride-tamsulosin and Elagolix have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Elagolix is a weak to moderate CYP3A4 inducer and may modestly reduce tamsulosin and dutasteride exposure. The clinical consequence is likely small.

How serious is the interaction between Dutasteride-tamsulosin and Elagolix?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor urinary symptom control. Raise the dose only if efficacy is clearly reduced.

What other medicines interact with Dutasteride-tamsulosin?

MediHelp also lists interactions of Dutasteride-tamsulosin with, for example, Alfuzosin, Amifostine, Atazanavir. The full list is on the Dutasteride-tamsulosin page.

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