Drug interactions
Elagolix + Flutamide
Severity: Minor
Elagolix and Flutamide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Elagolix is a weak to moderate CYP3A inducer and could modestly lower flutamide concentrations. The clinical relevance is likely small, and the combination is unusual because the indications rarely overlap.
What this interaction means in plain words
Elagolix and Flutamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Elagolix belongs to Musculoskeletal; Flutamide belongs to Endocrine.
Why it happens
Elagolix induces CYP3A4, modestly increasing flutamide metabolism.
What to do
Monitor for reduced flutamide effect if the combination is unavoidable. No routine dose change is needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Flutamide
Other interactions of Elagolix
- Cyclosporin + Elagolix Contraindicated
- Elagolix + Gemfibrozil Contraindicated
- Desogestrel-ethinyl estradiol + Elagolix Major
- Elagolix + Erythromycin Major
- Elagolix + Ethinyl estradiol-drospirenone Major
- Elagolix + Ethinyl estradiol-levonorgestrel Major
Frequently asked questions
Can I take Elagolix with Flutamide?
MediHelp rates the interaction as minor. Elagolix and Flutamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Elagolix is a weak to moderate CYP3A inducer and could modestly lower flutamide concentrations. The clinical relevance is likely small, and the combination is unusual because the indications rarely overlap.
How serious is the interaction between Elagolix and Flutamide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for reduced flutamide effect if the combination is unavoidable. No routine dose change is needed.
What other medicines interact with Flutamide?
MediHelp also lists interactions of Flutamide with, for example, Idelalisib, Levoketoconazole, Pexidartinib. The full list is on the Flutamide page.
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