Drug interactions
Eletriptan + Eliglustat
Severity: Minor
Eletriptan and Eliglustat: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Eliglustat inhibits P-glycoprotein and may modestly increase eletriptan concentrations. The clinical impact is likely small.
What this interaction means in plain words
Eletriptan and Eliglustat have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Eletriptan belongs to Central Nervous System; Eliglustat belongs to Miscellaneous.
Why it happens
Eliglustat inhibits P-gp efflux, increasing eletriptan absorption and reducing its elimination.
What to do
Monitor for increased triptan adverse effects and reduce the eletriptan dose if they occur.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Eletriptan
- Almotriptan + Eletriptan Contraindicated
- Atazanavir + Eletriptan Contraindicated
- Ceritinib + Eletriptan Contraindicated
- Clarithromycin + Eletriptan Contraindicated
- Cobicistat + Eletriptan Contraindicated
- Conivaptan + Eletriptan Contraindicated
Other interactions of Eliglustat
- Amiodarone + Eliglustat Contraindicated
- Clarithromycin + Eliglustat Contraindicated
- Dronedarone + Eliglustat Contraindicated
- Eliglustat + Itraconazole Contraindicated
- Eliglustat + Ketoconazole Contraindicated
- Eliglustat + Pimozide Contraindicated
Frequently asked questions
Can I take Eletriptan with Eliglustat?
MediHelp rates the interaction as minor. Eletriptan and Eliglustat have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Eliglustat inhibits P-glycoprotein and may modestly increase eletriptan concentrations. The clinical impact is likely small.
How serious is the interaction between Eletriptan and Eliglustat?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for increased triptan adverse effects and reduce the eletriptan dose if they occur.
What other medicines interact with Eletriptan?
MediHelp also lists interactions of Eletriptan with, for example, Almotriptan, Atazanavir, Ceritinib. The full list is on the Eletriptan page.
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