Drug interactions
Enalapril-hydrochlorothiazide + Verteporfin
Severity: Minor
Enalapril-hydrochlorothiazide and Verteporfin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hydrochlorothiazide is photosensitizing and could add to the photosensitivity that follows verteporfin photodynamic therapy. Patients may be more prone to skin reactions on sun exposure.
What this interaction means in plain words
Enalapril-hydrochlorothiazide and Verteporfin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Enalapril-hydrochlorothiazide belongs to Cardiovascular; Verteporfin belongs to Miscellaneous.
Why it happens
Additive photosensitization from two drugs that sensitize skin to light.
What to do
Counsel patients to avoid direct sunlight and bright indoor light and to use protective clothing for the period advised after verteporfin.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Enalapril-hydrochlorothiazide
- Aliskiren + Enalapril-hydrochlorothiazide Contraindicated
- Dofetilide + Enalapril-hydrochlorothiazide Contraindicated
- Enalapril-hydrochlorothiazide + Protein a column Contraindicated
- Enalapril-hydrochlorothiazide + Sacubitril / valsartan Contraindicated
- Amifostine + Enalapril-hydrochlorothiazide Major
- Amiloride + Enalapril-hydrochlorothiazide Major
Other interactions of Verteporfin
- Doxycycline + Verteporfin Moderate
- Griseofulvin + Verteporfin Moderate
- Minocycline + Verteporfin Moderate
- Tetracycline + Verteporfin Moderate
- Adapalene + Verteporfin Minor
- Amlodipine-hydrochlorothiazide-valsartan + Verteporfin Minor
Frequently asked questions
Can I take Enalapril-hydrochlorothiazide with Verteporfin?
MediHelp rates the interaction as minor. Enalapril-hydrochlorothiazide and Verteporfin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Hydrochlorothiazide is photosensitizing and could add to the photosensitivity that follows verteporfin photodynamic therapy. Patients may be more prone to skin reactions on sun exposure.
How serious is the interaction between Enalapril-hydrochlorothiazide and Verteporfin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to avoid direct sunlight and bright indoor light and to use protective clothing for the period advised after verteporfin.
What other medicines interact with Enalapril-hydrochlorothiazide?
MediHelp also lists interactions of Enalapril-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Protein a column. The full list is on the Enalapril-hydrochlorothiazide page.
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