Drug interactions
Entecavir + Oxaliplatin
Severity: Minor
Entecavir and Oxaliplatin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oxaliplatin can impair renal function in some patients, and entecavir is cleared mainly by the kidneys through filtration and tubular secretion. Reduced renal function may therefore raise entecavir exposure.
What this interaction means in plain words
Entecavir and Oxaliplatin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Entecavir belongs to Anti Virals; Oxaliplatin belongs to Oncology.
Why it happens
Possible reduced renal elimination of entecavir if oxaliplatin-related renal impairment occurs; this is a predicted rather than well-characterized effect.
What to do
Monitor serum creatinine during oxaliplatin therapy and adjust the entecavir dose to creatinine clearance if renal function declines.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Entecavir
Other interactions of Oxaliplatin
- Adenovirus types 4 and 7 live + Oxaliplatin Contraindicated
- Bcg vaccine live + Oxaliplatin Contraindicated
- Influenza virus vaccine quadrivalent intranasal + Oxaliplatin Contraindicated
- Measles mumps and rubella vaccine live + Oxaliplatin Contraindicated
- Measles mumps and rubella vaccine + Oxaliplatin Contraindicated
- Measles mumps rubella and varicella vaccine live + Oxaliplatin Contraindicated
Frequently asked questions
Can I take Entecavir with Oxaliplatin?
MediHelp rates the interaction as minor. Entecavir and Oxaliplatin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oxaliplatin can impair renal function in some patients, and entecavir is cleared mainly by the kidneys through filtration and tubular secretion. Reduced renal function may therefore raise entecavir exposure.
How serious is the interaction between Entecavir and Oxaliplatin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine during oxaliplatin therapy and adjust the entecavir dose to creatinine clearance if renal function declines.
What other medicines interact with Entecavir?
MediHelp also lists interactions of Entecavir with, for example, Alogliptin-metformin, Canagliflozin-metformin, Cidofovir. The full list is on the Entecavir page.
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