Drug interactions
Ephedrine + Indacaterol
Severity: Moderate
Ephedrine and Indacaterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ephedrine is a sympathomimetic with direct and indirect adrenergic activity. Combined with indacaterol it may cause additive tachycardia, palpitations, tremor and blood pressure elevation, which is more significant in cardiovascular disease.
What this interaction means in plain words
Ephedrine and Indacaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ephedrine belongs to Cardiovascular; Indacaterol belongs to Respiratory.
Why it happens
Additive pharmacodynamic adrenergic stimulation.
What to do
Monitor heart rate and blood pressure, and avoid concurrent use in patients with significant cardiovascular disease or arrhythmias.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol
Other interactions of Ephedrine
- Ephedrine + Isocarboxazid Contraindicated
- Ephedrine + Phenelzine Contraindicated
- Ephedrine + Procarbazine Contraindicated
- Ephedrine + Rasagiline Contraindicated
- Ephedrine + Selegiline Contraindicated
- Ephedrine + Tranylcypromine Contraindicated
Frequently asked questions
Can I take Ephedrine with Indacaterol?
MediHelp rates the interaction as moderate. Ephedrine and Indacaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ephedrine is a sympathomimetic with direct and indirect adrenergic activity. Combined with indacaterol it may cause additive tachycardia, palpitations, tremor and blood pressure elevation, which is more significant in cardiovascular disease.
How serious is the interaction between Ephedrine and Indacaterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and blood pressure, and avoid concurrent use in patients with significant cardiovascular disease or arrhythmias.
What other medicines interact with Indacaterol?
MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.
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