Drug interactions
Eprosartan-hydrochlorothiazide + Porfimer
Severity: Moderate
Eprosartan-hydrochlorothiazide and Porfimer: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Porfimer is a photosensitizer, and hydrochlorothiazide is itself photosensitizing. Together they may increase the risk or severity of phototoxic skin reactions after porfimer treatment.
What this interaction means in plain words
Eprosartan-hydrochlorothiazide and Porfimer can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Eprosartan-hydrochlorothiazide belongs to Cardiovascular; Porfimer belongs to Miscellaneous.
Why it happens
Additive photosensitivity from two agents that sensitize skin to light.
What to do
Reinforce strict light protection for the period specified in porfimer labeling and consider whether the thiazide can be temporarily replaced.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Eprosartan-hydrochlorothiazide
- Aliskiren + Eprosartan-hydrochlorothiazide Contraindicated
- Dofetilide + Eprosartan-hydrochlorothiazide Contraindicated
- Eprosartan-hydrochlorothiazide + Sparsentan Contraindicated
- Aceclofenac + Eprosartan-hydrochlorothiazide Major
- Aldesleukin + Eprosartan-hydrochlorothiazide Major
- Amifostine + Eprosartan-hydrochlorothiazide Major
Other interactions of Porfimer
Frequently asked questions
Can I take Eprosartan-hydrochlorothiazide with Porfimer?
MediHelp rates the interaction as moderate. Eprosartan-hydrochlorothiazide and Porfimer can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Porfimer is a photosensitizer, and hydrochlorothiazide is itself photosensitizing. Together they may increase the risk or severity of phototoxic skin reactions after porfimer treatment.
How serious is the interaction between Eprosartan-hydrochlorothiazide and Porfimer?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Reinforce strict light protection for the period specified in porfimer labeling and consider whether the thiazide can be temporarily replaced.
What other medicines interact with Eprosartan-hydrochlorothiazide?
MediHelp also lists interactions of Eprosartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Eprosartan-hydrochlorothiazide page.
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