Drug interactions
Ertugliflozin-sitagliptin + Prednisolone
Severity: Moderate
Ertugliflozin-sitagliptin and Prednisolone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Systemic prednisolone commonly raises blood glucose and can counteract ertugliflozin-sitagliptin. The effect depends on dose and duration.
What this interaction means in plain words
Ertugliflozin-sitagliptin and Prednisolone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ertugliflozin-sitagliptin belongs to Endocrine; Prednisolone belongs to Endocrine.
Why it happens
Glucocorticoids increase insulin resistance and hepatic glucose production.
What to do
Monitor blood glucose during therapy and adjust antidiabetic treatment as needed, including when tapering the steroid.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ertugliflozin-sitagliptin
Other interactions of Prednisolone
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- Measles mumps and rubella vaccine live + Prednisolone Contraindicated
- Measles mumps rubella and varicella vaccine live + Prednisolone Contraindicated
- Measles vaccine + Prednisolone Contraindicated
- Mifepristone + Prednisolone Contraindicated
- Prednisolone + Radium-223 dichloride Contraindicated
Frequently asked questions
Can I take Ertugliflozin-sitagliptin with Prednisolone?
MediHelp rates the interaction as moderate. Ertugliflozin-sitagliptin and Prednisolone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Systemic prednisolone commonly raises blood glucose and can counteract ertugliflozin-sitagliptin. The effect depends on dose and duration.
How serious is the interaction between Ertugliflozin-sitagliptin and Prednisolone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose during therapy and adjust antidiabetic treatment as needed, including when tapering the steroid.
What other medicines interact with Ertugliflozin-sitagliptin?
MediHelp also lists interactions of Ertugliflozin-sitagliptin with, for example, Albiglutide, Aripiprazole, Asenapine. The full list is on the Ertugliflozin-sitagliptin page.
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