Drug interactions
Finasteride + Fosaprepitant
Severity: Minor
Finasteride and Fosaprepitant: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fosaprepitant, a prodrug of aprepitant, is a moderate CYP3A4 inhibitor after single doses and may slightly raise finasteride levels. The effect is transient and unlikely to matter clinically.
What this interaction means in plain words
Finasteride and Fosaprepitant have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Finasteride belongs to Genitourinary; Fosaprepitant belongs to Gastrointestinal Tract.
Why it happens
Transient CYP3A4 inhibition reducing finasteride metabolism.
What to do
No action needed for the usual short antiemetic course.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Finasteride
- Finasteride + Levoketoconazole Moderate
- Finasteride + Nefazodone Moderate
- Finasteride + Rifampin Moderate
- Finasteride + St john's wort Moderate
- Amobarbital + Finasteride Minor
- Aprepitant + Finasteride Minor
Other interactions of Fosaprepitant
- Flibanserin + Fosaprepitant Contraindicated
- Fosaprepitant + Pimozide Contraindicated
- Alprazolam + Fosaprepitant Moderate
- Amiodarone + Fosaprepitant Moderate
- Amobarbital + Fosaprepitant Moderate
- Apalutamide + Fosaprepitant Moderate
Frequently asked questions
Can I take Finasteride with Fosaprepitant?
MediHelp rates the interaction as minor. Finasteride and Fosaprepitant have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Fosaprepitant, a prodrug of aprepitant, is a moderate CYP3A4 inhibitor after single doses and may slightly raise finasteride levels. The effect is transient and unlikely to matter clinically.
How serious is the interaction between Finasteride and Fosaprepitant?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action needed for the usual short antiemetic course.
What other medicines interact with Finasteride?
MediHelp also lists interactions of Finasteride with, for example, Levoketoconazole, Nefazodone, Rifampin. The full list is on the Finasteride page.
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