Drug interactions
Finasteride + Voriconazole
Severity: Minor
Finasteride and Voriconazole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Voriconazole is a strong CYP3A4 inhibitor and may increase finasteride exposure. The wide safety margin of finasteride means significant toxicity is unlikely.
What this interaction means in plain words
Finasteride and Voriconazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Finasteride belongs to Genitourinary; Voriconazole belongs to Anti Fungals.
Why it happens
Voriconazole inhibits CYP3A4-mediated finasteride metabolism.
What to do
No routine adjustment is required. Monitor for finasteride adverse effects during prolonged co-administration.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Finasteride
- Finasteride + Levoketoconazole Moderate
- Finasteride + Nefazodone Moderate
- Finasteride + Rifampin Moderate
- Finasteride + St john's wort Moderate
- Amobarbital + Finasteride Minor
- Aprepitant + Finasteride Minor
Other interactions of Voriconazole
- Avanafil + Voriconazole Contraindicated
- Butabarbital + Voriconazole Contraindicated
- Carbamazepine + Voriconazole Contraindicated
- Conivaptan + Voriconazole Contraindicated
- Dihydroergotamine intranasal + Voriconazole Contraindicated
- Dihydroergotamine + Voriconazole Contraindicated
Frequently asked questions
Can I take Finasteride with Voriconazole?
MediHelp rates the interaction as minor. Finasteride and Voriconazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Voriconazole is a strong CYP3A4 inhibitor and may increase finasteride exposure. The wide safety margin of finasteride means significant toxicity is unlikely.
How serious is the interaction between Finasteride and Voriconazole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is required. Monitor for finasteride adverse effects during prolonged co-administration.
What other medicines interact with Finasteride?
MediHelp also lists interactions of Finasteride with, for example, Levoketoconazole, Nefazodone, Rifampin. The full list is on the Finasteride page.
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