Drug interactions
Finerenone + Lovastatin
Severity: Minor
Finerenone and Lovastatin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lovastatin is a weak CYP3A4 inhibitor and may modestly raise finerenone levels, increasing the risk of hyperkalemia.
What this interaction means in plain words
Finerenone and Lovastatin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Finerenone belongs to Cardiovascular; Lovastatin belongs to Cardiovascular.
Why it happens
Weak inhibition of CYP3A4 by lovastatin reduces finerenone metabolism.
What to do
Monitor serum potassium when starting or changing either drug and adjust the finerenone dose per labeling.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Lovastatin
- Atazanavir + Lovastatin Contraindicated
- Clarithromycin + Lovastatin Contraindicated
- Cobicistat + Lovastatin Contraindicated
- Conivaptan + Lovastatin Contraindicated
- Darunavir + Lovastatin Contraindicated
- Elvitegravir / cobicistat / emtricitabine / tenofovir df + Lovastatin Contraindicated
Other interactions of Finerenone
- Carbamazepine + Finerenone Contraindicated
- Clarithromycin + Finerenone Contraindicated
- Ensitrelvir + Finerenone Contraindicated
- Finerenone + Itraconazole Contraindicated
- Finerenone + Ketoconazole Contraindicated
- Finerenone + Posaconazole Contraindicated
Frequently asked questions
Can I take Finerenone with Lovastatin?
MediHelp rates the interaction as minor. Finerenone and Lovastatin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Lovastatin is a weak CYP3A4 inhibitor and may modestly raise finerenone levels, increasing the risk of hyperkalemia.
How serious is the interaction between Finerenone and Lovastatin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium when starting or changing either drug and adjust the finerenone dose per labeling.
What other medicines interact with Lovastatin?
MediHelp also lists interactions of Lovastatin with, for example, Atazanavir, Clarithromycin, Cobicistat. The full list is on the Lovastatin page.
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