Drug interactions
Formoterol-mometasone + Prochlorperazine
Severity: Moderate
Formoterol-mometasone and Prochlorperazine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Prochlorperazine may prolong the QT interval, and formoterol can add to this effect and reduce serum potassium. The combination may modestly increase arrhythmia risk in susceptible patients.
What this interaction means in plain words
Formoterol-mometasone and Prochlorperazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Formoterol-mometasone belongs to Respiratory; Prochlorperazine belongs to Central Nervous System.
Why it happens
Additive QTc prolongation, with beta-2-agonist-induced hypokalemia as a potential contributor.
What to do
Monitor ECG and electrolytes in patients with cardiac risk factors. Correct hypokalemia before and during co-therapy.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Other interactions of Prochlorperazine
- Dronedarone + Prochlorperazine Contraindicated
- Ibutilide + Prochlorperazine Contraindicated
- Nilotinib + Prochlorperazine Contraindicated
- Pimozide + Prochlorperazine Contraindicated
- Prochlorperazine + Thioridazine Contraindicated
- Amiodarone + Prochlorperazine Major
Frequently asked questions
Can I take Formoterol-mometasone with Prochlorperazine?
MediHelp rates the interaction as moderate. Formoterol-mometasone and Prochlorperazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Prochlorperazine may prolong the QT interval, and formoterol can add to this effect and reduce serum potassium. The combination may modestly increase arrhythmia risk in susceptible patients.
How serious is the interaction between Formoterol-mometasone and Prochlorperazine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and electrolytes in patients with cardiac risk factors. Correct hypokalemia before and during co-therapy.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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