Drug interactions
Furosemide + Indacaterol
Severity: Moderate
Furosemide and Indacaterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Loop diuretics cause renal potassium loss, and beta-2 agonists can lower potassium further by shifting it into cells. The resulting hypokalemia may provoke arrhythmias, especially in patients taking digoxin or QT-prolonging drugs.
What this interaction means in plain words
Furosemide and Indacaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Furosemide belongs to Cardiovascular; Indacaterol belongs to Respiratory.
Why it happens
Diuretic-induced renal potassium wasting combined with beta-2 mediated intracellular potassium shift.
What to do
Monitor serum potassium and magnesium periodically and replace as needed. Take extra care during acute exacerbations or high diuretic doses.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol
Other interactions of Furosemide
- Amifostine + Furosemide Major
- Amikacin + Furosemide Major
- Carbenoxolone + Furosemide Major
- Cephaloridine + Furosemide Major
- Cisplatin + Furosemide Major
- Digoxin + Furosemide Major
Frequently asked questions
Can I take Furosemide with Indacaterol?
MediHelp rates the interaction as moderate. Furosemide and Indacaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Loop diuretics cause renal potassium loss, and beta-2 agonists can lower potassium further by shifting it into cells. The resulting hypokalemia may provoke arrhythmias, especially in patients taking digoxin or QT-prolonging drugs.
How serious is the interaction between Furosemide and Indacaterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and magnesium periodically and replace as needed. Take extra care during acute exacerbations or high diuretic doses.
What other medicines interact with Indacaterol?
MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.
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