Drug interactions
Gentamicin + Loratadine
Severity: Minor
Gentamicin and Loratadine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Gentamicin is eliminated by glomerular filtration and is not a meaningful P-glycoprotein substrate, so loratadine is not expected to alter its levels. No real clinical interaction is described.
What this interaction means in plain words
Gentamicin and Loratadine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Gentamicin belongs to Anti Bacterial; Loratadine belongs to Respiratory.
Why it happens
No established mechanism.
What to do
No action beyond usual gentamicin level and renal monitoring.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Loratadine
- Acrivastine + Loratadine Moderate
- Amobarbital + Loratadine Moderate
- Fentanyl + Loratadine Moderate
- Isocarboxazid + Loratadine Moderate
- Levoketoconazole + Loratadine Moderate
- Loratadine + Mavacamten Moderate
Other interactions of Gentamicin
- Cidofovir + Gentamicin Contraindicated
- Adefovir + Gentamicin Major
- Amikacin + Gentamicin Major
- Amlodipine-hydrochlorothiazide-valsartan + Gentamicin Major
- Amphotericin b deoxycholate + Gentamicin Major
- Amphotericin b + Gentamicin Major
Frequently asked questions
Can I take Gentamicin with Loratadine?
MediHelp rates the interaction as minor. Gentamicin and Loratadine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Gentamicin is eliminated by glomerular filtration and is not a meaningful P-glycoprotein substrate, so loratadine is not expected to alter its levels. No real clinical interaction is described.
How serious is the interaction between Gentamicin and Loratadine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action beyond usual gentamicin level and renal monitoring.
What other medicines interact with Loratadine?
MediHelp also lists interactions of Loratadine with, for example, Acrivastine, Amobarbital, Fentanyl. The full list is on the Loratadine page.
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