Drug interactions
Glucagon + Ipratropium
Severity: Minor
Glucagon and Ipratropium: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Anticholinergic drugs slow gastrointestinal motility, and glucagon also inhibits GI motility when used for diagnostic radiology. Together they may increase the risk of GI adverse effects such as nausea, vomiting and reduced motility. Systemic absorption of inhaled ipratropium is low, so the risk is smaller than with oral anticholinergics.
What this interaction means in plain words
Glucagon and Ipratropium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Glucagon belongs to Endocrine; Ipratropium belongs to Respiratory.
Why it happens
Additive inhibition of gastrointestinal motility via anticholinergic and glucagon effects.
What to do
No action is needed with inhaled ipratropium for routine use. If glucagon is used as a GI diagnostic aid, monitor for GI symptoms.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ipratropium
- Aclidinium + Ipratropium Moderate
- Benztropine + Ipratropium Moderate
- Bethanechol + Ipratropium Moderate
- Cevimeline + Ipratropium Moderate
- Chlorpromazine + Ipratropium Moderate
- Clomipramine + Ipratropium Moderate
Other interactions of Glucagon
- Atropine + Glucagon Moderate
- Benztropine + Glucagon Moderate
- Dicyclomine + Glucagon Moderate
- Diphenoxylate-atropine + Glucagon Moderate
- Glucagon + Glycopyrrolate Moderate
- Glucagon + Glycopyrronium Moderate
Frequently asked questions
Can I take Glucagon with Ipratropium?
MediHelp rates the interaction as minor. Glucagon and Ipratropium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Anticholinergic drugs slow gastrointestinal motility, and glucagon also inhibits GI motility when used for diagnostic radiology. Together they may increase the risk of GI adverse effects such as nausea, vomiting and reduced motility. Systemic absorption of inhaled ipratropium is low, so the risk is smaller than with oral anticholinergics.
How serious is the interaction between Glucagon and Ipratropium?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is needed with inhaled ipratropium for routine use. If glucagon is used as a GI diagnostic aid, monitor for GI symptoms.
What other medicines interact with Ipratropium?
MediHelp also lists interactions of Ipratropium with, for example, Aclidinium, Benztropine, Bethanechol. The full list is on the Ipratropium page.
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