Drug interactions
Goserelin + Indacaterol-glycopyrronium
Severity: Moderate
Goserelin and Indacaterol-glycopyrronium: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Androgen deprivation therapy with goserelin can prolong the QT interval. Indacaterol may add modest repolarization effects or lower potassium, which could increase arrhythmia risk, especially in patients with other risk factors.
What this interaction means in plain words
Goserelin and Indacaterol-glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Goserelin belongs to Endocrine; Indacaterol-glycopyrronium belongs to Respiratory.
Why it happens
Additive effects on cardiac repolarization.
What to do
Consider baseline and periodic ECG and electrolytes in patients with cardiac risk factors or other QT-prolonging drugs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol-glycopyrronium
Other interactions of Goserelin
Frequently asked questions
Can I take Goserelin with Indacaterol-glycopyrronium?
MediHelp rates the interaction as moderate. Goserelin and Indacaterol-glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Androgen deprivation therapy with goserelin can prolong the QT interval. Indacaterol may add modest repolarization effects or lower potassium, which could increase arrhythmia risk, especially in patients with other risk factors.
How serious is the interaction between Goserelin and Indacaterol-glycopyrronium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider baseline and periodic ECG and electrolytes in patients with cardiac risk factors or other QT-prolonging drugs.
What other medicines interact with Indacaterol-glycopyrronium?
MediHelp also lists interactions of Indacaterol-glycopyrronium with, for example, Amisulpride, Arformoterol, Arsenic trioxide. The full list is on the Indacaterol-glycopyrronium page.
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