Drug interactions
Granisetron + Triclabendazole
Severity: Moderate
Granisetron and Triclabendazole: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Triclabendazole can prolong QT, and granisetron may add a small effect. The risk is higher with electrolyte abnormalities, bradycardia or congenital long QT.
What this interaction means in plain words
Granisetron and Triclabendazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Granisetron belongs to Gastrointestinal Tract; Triclabendazole belongs to Anti Parasitic.
Why it happens
Additive QT interval prolongation.
What to do
Avoid in patients with known long QT or other major risk factors, or obtain an ECG and correct electrolytes before use. Consider another antiemetic if one is needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Granisetron
- Apomorphine + Granisetron Contraindicated
- Amiodarone + Granisetron Major
- Amisulpride + Granisetron Major
- Arsenic trioxide + Granisetron Major
- Artemether / lumefantrine + Granisetron Major
- Artemether + Granisetron Major
Other interactions of Triclabendazole
Frequently asked questions
Can I take Granisetron with Triclabendazole?
MediHelp rates the interaction as moderate. Granisetron and Triclabendazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Triclabendazole can prolong QT, and granisetron may add a small effect. The risk is higher with electrolyte abnormalities, bradycardia or congenital long QT.
How serious is the interaction between Granisetron and Triclabendazole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid in patients with known long QT or other major risk factors, or obtain an ECG and correct electrolytes before use. Consider another antiemetic if one is needed.
What other medicines interact with Granisetron?
MediHelp also lists interactions of Granisetron with, for example, Apomorphine, Amiodarone, Amisulpride. The full list is on the Granisetron page.
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