Drug interactions
Griseofulvin + Porfimer
Severity: Moderate
Griseofulvin and Porfimer: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both agents can cause photosensitivity. Using griseofulvin around porfimer photodynamic therapy may worsen skin and eye photoreactions on light exposure.
What this interaction means in plain words
Griseofulvin and Porfimer can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Griseofulvin belongs to Anti Fungals; Porfimer belongs to Miscellaneous.
Why it happens
Additive phototoxic effects from two photosensitizing drugs.
What to do
Counsel strict light protection for the period porfimer remains active, and avoid griseofulvin during that time if possible.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Griseofulvin
Other interactions of Porfimer
Frequently asked questions
Can I take Griseofulvin with Porfimer?
MediHelp rates the interaction as moderate. Griseofulvin and Porfimer can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both agents can cause photosensitivity. Using griseofulvin around porfimer photodynamic therapy may worsen skin and eye photoreactions on light exposure.
How serious is the interaction between Griseofulvin and Porfimer?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel strict light protection for the period porfimer remains active, and avoid griseofulvin during that time if possible.
What other medicines interact with Griseofulvin?
MediHelp also lists interactions of Griseofulvin with, for example, Cyclosporine, Cyclosporin, Desogestrel-ethinyl estradiol. The full list is on the Griseofulvin page.
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