Drug interactions
Haloperidol + Indacaterol
Severity: Moderate
Haloperidol and Indacaterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Haloperidol, particularly at higher doses or intravenously, prolongs the QT interval and can cause torsades de pointes. Indacaterol may add cardiac stimulation and hypokalemia, further raising arrhythmia risk.
What this interaction means in plain words
Haloperidol and Indacaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Haloperidol belongs to Central Nervous System; Indacaterol belongs to Respiratory.
Why it happens
Additive QT prolongation, with beta-2 agonist related hypokalemia.
What to do
Use the lowest effective haloperidol dose and obtain a baseline and follow-up ECG in at-risk patients. Keep potassium and magnesium within normal range.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol
Other interactions of Haloperidol
- Dofetilide + Haloperidol Contraindicated
- Dronedarone + Haloperidol Contraindicated
- Haloperidol + Ibutilide Contraindicated
- Haloperidol + Levoketoconazole Contraindicated
- Haloperidol + Panobinostat Contraindicated
- Haloperidol + Pimozide Contraindicated
Frequently asked questions
Can I take Haloperidol with Indacaterol?
MediHelp rates the interaction as moderate. Haloperidol and Indacaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Haloperidol, particularly at higher doses or intravenously, prolongs the QT interval and can cause torsades de pointes. Indacaterol may add cardiac stimulation and hypokalemia, further raising arrhythmia risk.
How serious is the interaction between Haloperidol and Indacaterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective haloperidol dose and obtain a baseline and follow-up ECG in at-risk patients. Keep potassium and magnesium within normal range.
What other medicines interact with Indacaterol?
MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.
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