Drug interactions
Haloperidol + Levamlodipine
Severity: Minor
Haloperidol and Levamlodipine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Levamlodipine is metabolized by CYP3A4, but haloperidol is at most a weak inhibitor, so exposure is unlikely to change much. Both agents can lower blood pressure, so additive hypotension is possible.
What this interaction means in plain words
Haloperidol and Levamlodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Haloperidol belongs to Central Nervous System; Levamlodipine belongs to Cardiovascular.
Why it happens
Possible weak CYP3A4 inhibition plus additive hypotensive effects.
What to do
Monitor blood pressure and for edema or dizziness, particularly in older patients.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Haloperidol
- Dofetilide + Haloperidol Contraindicated
- Dronedarone + Haloperidol Contraindicated
- Haloperidol + Ibutilide Contraindicated
- Haloperidol + Levoketoconazole Contraindicated
- Haloperidol + Panobinostat Contraindicated
- Haloperidol + Pimozide Contraindicated
Other interactions of Levamlodipine
- Dantrolene + Levamlodipine Major
- Amiodarone + Levamlodipine Moderate
- Amobarbital + Levamlodipine Moderate
- Apalutamide + Levamlodipine Moderate
- Aprepitant + Levamlodipine Moderate
- Armodafinil + Levamlodipine Moderate
Frequently asked questions
Can I take Haloperidol with Levamlodipine?
MediHelp rates the interaction as minor. Haloperidol and Levamlodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Levamlodipine is metabolized by CYP3A4, but haloperidol is at most a weak inhibitor, so exposure is unlikely to change much. Both agents can lower blood pressure, so additive hypotension is possible.
How serious is the interaction between Haloperidol and Levamlodipine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and for edema or dizziness, particularly in older patients.
What other medicines interact with Haloperidol?
MediHelp also lists interactions of Haloperidol with, for example, Dofetilide, Dronedarone, Ibutilide. The full list is on the Haloperidol page.
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