Drug interactions
Haloperidol + Ozanimod
Severity: Moderate
Haloperidol and Ozanimod: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ozanimod can slow heart rate and atrioventricular conduction, and haloperidol prolongs the QT interval. Together they may increase the risk of bradycardia-related torsades de pointes.
What this interaction means in plain words
Haloperidol and Ozanimod can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Haloperidol belongs to Central Nervous System; Ozanimod belongs to Central Nervous System.
Why it happens
Additive effects of heart rate slowing and QTc prolongation.
What to do
Obtain a baseline ECG before starting ozanimod and seek cardiology advice if QT-prolonging drugs cannot be avoided; monitor heart rate and QTc.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Haloperidol
- Dofetilide + Haloperidol Contraindicated
- Dronedarone + Haloperidol Contraindicated
- Haloperidol + Ibutilide Contraindicated
- Haloperidol + Levoketoconazole Contraindicated
- Haloperidol + Panobinostat Contraindicated
- Haloperidol + Pimozide Contraindicated
Other interactions of Ozanimod
- Isocarboxazid + Ozanimod Contraindicated
- Linezolid + Ozanimod Contraindicated
- Ozanimod + Phenelzine Contraindicated
- Ozanimod + Procarbazine Contraindicated
- Ozanimod + Rasagiline Contraindicated
- Ozanimod + Safinamide Contraindicated
Frequently asked questions
Can I take Haloperidol with Ozanimod?
MediHelp rates the interaction as moderate. Haloperidol and Ozanimod can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ozanimod can slow heart rate and atrioventricular conduction, and haloperidol prolongs the QT interval. Together they may increase the risk of bradycardia-related torsades de pointes.
How serious is the interaction between Haloperidol and Ozanimod?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG before starting ozanimod and seek cardiology advice if QT-prolonging drugs cannot be avoided; monitor heart rate and QTc.
What other medicines interact with Haloperidol?
MediHelp also lists interactions of Haloperidol with, for example, Dofetilide, Dronedarone, Ibutilide. The full list is on the Haloperidol page.
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