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Drug interactions

Haloperidol + Ozanimod

Severity: Moderate

Haloperidol and Ozanimod: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Ozanimod can slow heart rate and atrioventricular conduction, and haloperidol prolongs the QT interval. Together they may increase the risk of bradycardia-related torsades de pointes.

What this interaction means in plain words

Haloperidol and Ozanimod can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Haloperidol belongs to Central Nervous System; Ozanimod belongs to Central Nervous System.

Evidence level: Low

Why it happens

Additive effects of heart rate slowing and QTc prolongation.

What to do

Obtain a baseline ECG before starting ozanimod and seek cardiology advice if QT-prolonging drugs cannot be avoided; monitor heart rate and QTc.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Haloperidol with Ozanimod?

MediHelp rates the interaction as moderate. Haloperidol and Ozanimod can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ozanimod can slow heart rate and atrioventricular conduction, and haloperidol prolongs the QT interval. Together they may increase the risk of bradycardia-related torsades de pointes.

How serious is the interaction between Haloperidol and Ozanimod?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG before starting ozanimod and seek cardiology advice if QT-prolonging drugs cannot be avoided; monitor heart rate and QTc.

What other medicines interact with Haloperidol?

MediHelp also lists interactions of Haloperidol with, for example, Dofetilide, Dronedarone, Ibutilide. The full list is on the Haloperidol page.

Full monographs, dosing and an interaction checker in the MediHelp app

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