Drug interactions
Hawthorn + Lidocaine
Severity: Minor
Hawthorn and Lidocaine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hawthorn has cardioactive properties, including positive inotropic, vasodilatory and possible antiarrhythmic effects. Combined with lidocaine, additive effects on cardiac conduction and blood pressure are theoretically possible, but clinical data are scarce.
What this interaction means in plain words
Hawthorn and Lidocaine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Hawthorn belongs to Gastrointestinal Tract; Lidocaine belongs to Cardiovascular.
Why it happens
Theoretical additive cardiovascular pharmacodynamic effects; no established pharmacokinetic mechanism.
What to do
No routine change is needed; monitor heart rate and blood pressure when systemic lidocaine is given to patients taking hawthorn.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Lidocaine
- Bupivacaine liposome + Lidocaine Major
- Disopyramide + Lidocaine Major
- Ex vivo expanded autologous human corneal epithelial cells containing stem cells + Lidocaine Major
- Lidocaine + Nirmatrelvir / ritonavir Major
- Lidocaine + Ombitasvir / paritaprevir / ritonavir and dasabuvir Major
- Lidocaine + Pimozide Major
Other interactions of Hawthorn
- Amiodarone + Hawthorn Moderate
- Digoxin + Hawthorn Moderate
- Disopyramide + Hawthorn Moderate
- Encainide + Hawthorn Moderate
- Hawthorn + Ibutilide Moderate
- Hawthorn + Procainamide Moderate
Frequently asked questions
Can I take Hawthorn with Lidocaine?
MediHelp rates the interaction as minor. Hawthorn and Lidocaine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Hawthorn has cardioactive properties, including positive inotropic, vasodilatory and possible antiarrhythmic effects. Combined with lidocaine, additive effects on cardiac conduction and blood pressure are theoretically possible, but clinical data are scarce.
How serious is the interaction between Hawthorn and Lidocaine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; monitor heart rate and blood pressure when systemic lidocaine is given to patients taking hawthorn.
What other medicines interact with Lidocaine?
MediHelp also lists interactions of Lidocaine with, for example, Bupivacaine liposome, Disopyramide, Ex vivo expanded autologous human corneal epithelial cells containing stem cells. The full list is on the Lidocaine page.
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