Drug interactions
Hawthorn + Primidone
Severity: Minor
Hawthorn and Primidone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hawthorn may have mild sedative properties. With primidone, which is metabolized partly to phenobarbital, additive drowsiness is theoretically possible.
What this interaction means in plain words
Hawthorn and Primidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Hawthorn belongs to Gastrointestinal Tract; Primidone belongs to Central Nervous System.
Why it happens
Theoretical additive CNS depression.
What to do
Counsel on additive sedation and monitor for excess drowsiness.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Hawthorn and Primidone, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Hawthorn
- Amiodarone + Hawthorn Moderate
- Digoxin + Hawthorn Moderate
- Disopyramide + Hawthorn Moderate
- Encainide + Hawthorn Moderate
- Hawthorn + Ibutilide Moderate
- Hawthorn + Procainamide Moderate
Other interactions of Primidone
- Lorlatinib + Primidone Contraindicated
- Lurasidone + Primidone Contraindicated
- Primidone + Ranolazine Contraindicated
- Primidone + Sofosbuvir-velpatasvir-voxilaprevir Contraindicated
- Primidone + Voriconazole Contraindicated
- Abiraterone + Primidone Major
Frequently asked questions
Can I take Hawthorn with Primidone?
MediHelp rates the interaction as minor. Hawthorn and Primidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Hawthorn may have mild sedative properties. With primidone, which is metabolized partly to phenobarbital, additive drowsiness is theoretically possible.
How serious is the interaction between Hawthorn and Primidone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel on additive sedation and monitor for excess drowsiness.
What other medicines interact with Hawthorn?
MediHelp also lists interactions of Hawthorn with, for example, Amiodarone, Digoxin, Disopyramide. The full list is on the Hawthorn page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
