Drug interactions
Hydrochlorothiazide-telmisartan + Porfimer
Severity: Moderate
Hydrochlorothiazide-telmisartan and Porfimer: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hydrochlorothiazide is a photosensitizing drug, and porfimer causes marked photosensitivity after photodynamic therapy. Using both can increase the risk or severity of skin phototoxic reactions during the period of sensitivity.
What this interaction means in plain words
Hydrochlorothiazide-telmisartan and Porfimer can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Hydrochlorothiazide-telmisartan belongs to Cardiovascular; Porfimer belongs to Miscellaneous.
Why it happens
Additive photosensitizing effects of a thiazide and a photosensitizer.
What to do
Counsel strict sun and bright-light protection for the entire photosensitivity period after porfimer. Consider whether the thiazide can be paused or replaced in this period.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Hydrochlorothiazide-telmisartan
- Aliskiren + Hydrochlorothiazide-telmisartan Contraindicated
- Dofetilide + Hydrochlorothiazide-telmisartan Contraindicated
- Hydrochlorothiazide-telmisartan + Sparsentan Contraindicated
- Aldesleukin + Hydrochlorothiazide-telmisartan Major
- Amifostine + Hydrochlorothiazide-telmisartan Major
- Amiloride + Hydrochlorothiazide-telmisartan Major
Other interactions of Porfimer
Frequently asked questions
Can I take Hydrochlorothiazide-telmisartan with Porfimer?
MediHelp rates the interaction as moderate. Hydrochlorothiazide-telmisartan and Porfimer can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Hydrochlorothiazide is a photosensitizing drug, and porfimer causes marked photosensitivity after photodynamic therapy. Using both can increase the risk or severity of skin phototoxic reactions during the period of sensitivity.
How serious is the interaction between Hydrochlorothiazide-telmisartan and Porfimer?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel strict sun and bright-light protection for the entire photosensitivity period after porfimer. Consider whether the thiazide can be paused or replaced in this period.
What other medicines interact with Hydrochlorothiazide-telmisartan?
MediHelp also lists interactions of Hydrochlorothiazide-telmisartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-telmisartan page.
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