Drug interactions
Hydroxychloroquine + Mycophenolate mofetil
Severity: Minor
Hydroxychloroquine and Mycophenolate mofetil: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hydroxychloroquine is commonly combined with mycophenolate in lupus, and its immunomodulatory effect is mild. Any added infection risk is small and the combination is generally considered acceptable.
What this interaction means in plain words
Hydroxychloroquine and Mycophenolate mofetil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Hydroxychloroquine belongs to Musculoskeletal; Mycophenolate mofetil belongs to Miscellaneous.
Why it happens
Weak additive immunomodulation; hydroxychloroquine is not meaningfully immunosuppressive in the way of cytotoxic agents.
What to do
No change in therapy is needed; continue routine infection surveillance and blood count monitoring for mycophenolate.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Mycophenolate mofetil
- Adenovirus types 4 and 7 live + Mycophenolate mofetil Contraindicated
- Bcg vaccine live + Mycophenolate mofetil Contraindicated
- Influenza virus vaccine quadrivalent intranasal + Mycophenolate mofetil Contraindicated
- Measles mumps and rubella vaccine live + Mycophenolate mofetil Contraindicated
- Measles mumps rubella and varicella vaccine live + Mycophenolate mofetil Contraindicated
- Measles vaccine + Mycophenolate mofetil Contraindicated
Other interactions of Hydroxychloroquine
- Arsenic trioxide + Hydroxychloroquine Contraindicated
- Cisapride + Hydroxychloroquine Contraindicated
- Dronedarone + Hydroxychloroquine Contraindicated
- Hydroxychloroquine + Pimozide Contraindicated
- Hydroxychloroquine + Thioridazine Contraindicated
- Hydroxychloroquine + Vandetanib Contraindicated
Frequently asked questions
Can I take Hydroxychloroquine with Mycophenolate mofetil?
MediHelp rates the interaction as minor. Hydroxychloroquine and Mycophenolate mofetil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Hydroxychloroquine is commonly combined with mycophenolate in lupus, and its immunomodulatory effect is mild. Any added infection risk is small and the combination is generally considered acceptable.
How serious is the interaction between Hydroxychloroquine and Mycophenolate mofetil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No change in therapy is needed; continue routine infection surveillance and blood count monitoring for mycophenolate.
What other medicines interact with Mycophenolate mofetil?
MediHelp also lists interactions of Mycophenolate mofetil with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Mycophenolate mofetil page.
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