Drug interactions
Hydroxyzine + Triclabendazole
Severity: Moderate
Hydroxyzine and Triclabendazole: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both agents can prolong the QT interval, so together they may raise the risk of ventricular arrhythmia, particularly with electrolyte abnormalities or heart disease.
What this interaction means in plain words
Hydroxyzine and Triclabendazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Hydroxyzine belongs to Respiratory; Triclabendazole belongs to Anti Parasitic.
Why it happens
Additive QT prolongation.
What to do
Obtain an ECG and check potassium and magnesium if the combination is needed. Avoid in patients with congenital long QT syndrome.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Hydroxyzine
- Droperidol + Hydroxyzine Contraindicated
- Hydroxyzine + Pimozide Contraindicated
- Hydroxyzine + Thioridazine Contraindicated
- Hydroxyzine + Vandetanib Contraindicated
- Alfentanil + Hydroxyzine Major
- Amiodarone + Hydroxyzine Major
Other interactions of Triclabendazole
Frequently asked questions
Can I take Hydroxyzine with Triclabendazole?
MediHelp rates the interaction as moderate. Hydroxyzine and Triclabendazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both agents can prolong the QT interval, so together they may raise the risk of ventricular arrhythmia, particularly with electrolyte abnormalities or heart disease.
How serious is the interaction between Hydroxyzine and Triclabendazole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain an ECG and check potassium and magnesium if the combination is needed. Avoid in patients with congenital long QT syndrome.
What other medicines interact with Hydroxyzine?
MediHelp also lists interactions of Hydroxyzine with, for example, Droperidol, Pimozide, Thioridazine. The full list is on the Hydroxyzine page.
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