Drug interactions
Icatibant + Moexipril
Severity: Minor
Icatibant and Moexipril: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Icatibant blocks bradykinin B2 receptors, and bradykinin contributes to part of the effect of ACE inhibitors. The antihypertensive effect of the ACE inhibitor could be reduced, and the ACE inhibitor itself is a recognised cause of bradykinin-mediated angioedema that icatibant may be used to treat.
What this interaction means in plain words
Icatibant and Moexipril have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Icatibant belongs to Miscellaneous; Moexipril belongs to Cardiovascular.
Why it happens
Pharmacodynamic antagonism of bradykinin B2 receptor-mediated effects of ACE inhibition.
What to do
Monitor blood pressure after icatibant use. Stop the ACE inhibitor if angioedema occurred.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Icatibant and Moexipril, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Moexipril
- Aliskiren + Moexipril Contraindicated
- Moexipril + Protein a column Contraindicated
- Moexipril + Sacubitril / valsartan Contraindicated
- Moexipril + Sacubitril-valsartan Contraindicated
- Amifostine + Moexipril Major
- Amiloride + Moexipril Major
Other interactions of Icatibant
Frequently asked questions
Can I take Icatibant with Moexipril?
MediHelp rates the interaction as minor. Icatibant and Moexipril have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Icatibant blocks bradykinin B2 receptors, and bradykinin contributes to part of the effect of ACE inhibitors. The antihypertensive effect of the ACE inhibitor could be reduced, and the ACE inhibitor itself is a recognised cause of bradykinin-mediated angioedema that icatibant may be used to treat.
How serious is the interaction between Icatibant and Moexipril?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure after icatibant use. Stop the ACE inhibitor if angioedema occurred.
What other medicines interact with Moexipril?
MediHelp also lists interactions of Moexipril with, for example, Aliskiren, Protein a column, Sacubitril / valsartan. The full list is on the Moexipril page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
