Drug interactions
Iloperidone + Indacaterol
Severity: Moderate
Iloperidone and Indacaterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Iloperidone prolongs the QT interval, and indacaterol may contribute through its cardiac effects and potassium lowering. Together they may increase the risk of ventricular arrhythmias.
What this interaction means in plain words
Iloperidone and Indacaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Iloperidone belongs to Central Nervous System; Indacaterol belongs to Respiratory.
Why it happens
Additive QT prolongation, with beta-agonist-induced hypokalemia as a possible contributor.
What to do
Monitor ECG and electrolytes, especially in patients with cardiac disease or other QT-prolonging drugs. Consider an alternative if QTc becomes significantly prolonged.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol
Other interactions of Iloperidone
- Iloperidone + Thioridazine Contraindicated
- Alfuzosin + Iloperidone Major
- Amiodarone + Iloperidone Major
- Amisulpride + Iloperidone Major
- Amitriptyline + Iloperidone Major
- Anagrelide + Iloperidone Major
Frequently asked questions
Can I take Iloperidone with Indacaterol?
MediHelp rates the interaction as moderate. Iloperidone and Indacaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Iloperidone prolongs the QT interval, and indacaterol may contribute through its cardiac effects and potassium lowering. Together they may increase the risk of ventricular arrhythmias.
How serious is the interaction between Iloperidone and Indacaterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and electrolytes, especially in patients with cardiac disease or other QT-prolonging drugs. Consider an alternative if QTc becomes significantly prolonged.
What other medicines interact with Indacaterol?
MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.
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