Drug interactions
Indacaterol + Macimorelin
Severity: Moderate
Indacaterol and Macimorelin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Macimorelin causes a small QT increase, and indacaterol may add to cardiac effects. The combination may raise the risk of torsades de pointes, particularly in susceptible patients.
What this interaction means in plain words
Indacaterol and Macimorelin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Indacaterol belongs to Respiratory; Macimorelin belongs to Endocrine.
Why it happens
Additive QT prolongation.
What to do
Avoid or delay macimorelin testing while on QT-prolonging drugs where possible, or obtain an ECG and correct electrolytes beforehand.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol
Other interactions of Macimorelin
Frequently asked questions
Can I take Indacaterol with Macimorelin?
MediHelp rates the interaction as moderate. Indacaterol and Macimorelin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Macimorelin causes a small QT increase, and indacaterol may add to cardiac effects. The combination may raise the risk of torsades de pointes, particularly in susceptible patients.
How serious is the interaction between Indacaterol and Macimorelin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid or delay macimorelin testing while on QT-prolonging drugs where possible, or obtain an ECG and correct electrolytes beforehand.
What other medicines interact with Indacaterol?
MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.
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