Drug interactions
Indacaterol + Mefloquine
Severity: Moderate
Indacaterol and Mefloquine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Mefloquine can alter cardiac conduction and prolong QT, and indacaterol may add arrhythmic risk through hypokalemia and tachycardia.
What this interaction means in plain words
Indacaterol and Mefloquine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Indacaterol belongs to Respiratory; Mefloquine belongs to Anti Parasitic.
Why it happens
Additive effects on cardiac repolarization plus beta-2 agonist-induced hypokalemia.
What to do
Obtain an ECG and correct electrolytes before use in patients with cardiac risk. Consider alternative antimalarial prophylaxis if QT risk is significant.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol
Other interactions of Mefloquine
- Arsenic trioxide + Mefloquine Contraindicated
- Dronedarone + Mefloquine Contraindicated
- Ibutilide + Mefloquine Contraindicated
- Levoketoconazole + Mefloquine Contraindicated
- Mefloquine + Nilotinib Contraindicated
- Mefloquine + Pimozide Contraindicated
Frequently asked questions
Can I take Indacaterol with Mefloquine?
MediHelp rates the interaction as moderate. Indacaterol and Mefloquine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Mefloquine can alter cardiac conduction and prolong QT, and indacaterol may add arrhythmic risk through hypokalemia and tachycardia.
How serious is the interaction between Indacaterol and Mefloquine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain an ECG and correct electrolytes before use in patients with cardiac risk. Consider alternative antimalarial prophylaxis if QT risk is significant.
What other medicines interact with Indacaterol?
MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.
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