Drug interactions
Indacaterol + Voriconazole
Severity: Moderate
Indacaterol and Voriconazole: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Voriconazole is associated with QT prolongation and torsades de pointes. Indacaterol may add to this risk through beta2-mediated cardiac effects and potassium lowering. Voriconazole also inhibits CYP3A4 and P-gp, which may modestly raise indacaterol exposure.
What this interaction means in plain words
Indacaterol and Voriconazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Indacaterol belongs to Respiratory; Voriconazole belongs to Anti Fungals.
Why it happens
Additive QT prolongation and beta2-agonist cardiac effects, with possible increased indacaterol exposure from CYP3A4/P-gp inhibition.
What to do
Monitor ECG and correct potassium and magnesium before and during co-therapy. Watch for palpitations, tremor and tachycardia.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Indacaterol and Voriconazole, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Indacaterol
Other interactions of Voriconazole
- Avanafil + Voriconazole Contraindicated
- Butabarbital + Voriconazole Contraindicated
- Carbamazepine + Voriconazole Contraindicated
- Conivaptan + Voriconazole Contraindicated
- Dihydroergotamine intranasal + Voriconazole Contraindicated
- Dihydroergotamine + Voriconazole Contraindicated
Frequently asked questions
Can I take Indacaterol with Voriconazole?
MediHelp rates the interaction as moderate. Indacaterol and Voriconazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Voriconazole is associated with QT prolongation and torsades de pointes. Indacaterol may add to this risk through beta2-mediated cardiac effects and potassium lowering. Voriconazole also inhibits CYP3A4 and P-gp, which may modestly raise indacaterol exposure.
How serious is the interaction between Indacaterol and Voriconazole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and correct potassium and magnesium before and during co-therapy. Watch for palpitations, tremor and tachycardia.
What other medicines interact with Indacaterol?
MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
