Drug interactions
Iron sucrose + Moxifloxacin
Severity: Minor
Iron sucrose and Moxifloxacin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral iron binds moxifloxacin in the gut and reduces its absorption, which can lead to subtherapeutic antibiotic levels and treatment failure. Iron sucrose is given intravenously, so this chelation does not apply to it, and the interaction only matters with oral iron salts.
What this interaction means in plain words
Iron sucrose and Moxifloxacin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Iron sucrose belongs to Miscellaneous; Moxifloxacin belongs to Anti Bacterial.
Why it happens
Chelation of the quinolone by polyvalent iron cations in the gastrointestinal tract, which occurs only with oral iron products.
What to do
With intravenous iron sucrose no separation is needed. If oral iron is used instead, give moxifloxacin at least 4 hours before or 8 hours after the iron.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Moxifloxacin
- Amiodarone + Moxifloxacin Contraindicated
- Arsenic trioxide + Moxifloxacin Contraindicated
- Disopyramide + Moxifloxacin Contraindicated
- Dofetilide + Moxifloxacin Contraindicated
- Dronedarone + Moxifloxacin Contraindicated
- Droperidol + Moxifloxacin Contraindicated
Other interactions of Iron sucrose
- Dextrose 5% + Iron sucrose Contraindicated
- Deferasirox + Iron sucrose Moderate
- Deferiprone + Iron sucrose Moderate
- Deferoxamine + Iron sucrose Moderate
- Amlodipine-benazepril + Iron sucrose Minor
- Benazepril + Iron sucrose Minor
Frequently asked questions
Can I take Iron sucrose with Moxifloxacin?
MediHelp rates the interaction as minor. Iron sucrose and Moxifloxacin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral iron binds moxifloxacin in the gut and reduces its absorption, which can lead to subtherapeutic antibiotic levels and treatment failure. Iron sucrose is given intravenously, so this chelation does not apply to it, and the interaction only matters with oral iron salts.
How serious is the interaction between Iron sucrose and Moxifloxacin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: With intravenous iron sucrose no separation is needed. If oral iron is used instead, give moxifloxacin at least 4 hours before or 8 hours after the iron.
What other medicines interact with Moxifloxacin?
MediHelp also lists interactions of Moxifloxacin with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Moxifloxacin page.
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