Drug interactions
Isavuconazonium + Propofol
Severity: Minor
Isavuconazonium and Propofol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Propofol is not a recognized CYP3A4 inhibitor, so an increase in isavuconazole exposure is not expected. No clinically significant interaction is established.
What this interaction means in plain words
Isavuconazonium and Propofol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Isavuconazonium belongs to Anti Fungals; Propofol belongs to Central Nervous System.
Why it happens
No established mechanism; propofol does not meaningfully inhibit CYP3A4.
What to do
No dose adjustment is needed; use routine monitoring.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Propofol
Other interactions of Isavuconazonium
- Amobarbital + Isavuconazonium Contraindicated
- Apalutamide + Isavuconazonium Contraindicated
- Carbamazepine + Isavuconazonium Contraindicated
- Cisapride + Isavuconazonium Contraindicated
- Efavirenz + Isavuconazonium Contraindicated
- Enzalutamide + Isavuconazonium Contraindicated
Frequently asked questions
Can I take Isavuconazonium with Propofol?
MediHelp rates the interaction as minor. Isavuconazonium and Propofol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Propofol is not a recognized CYP3A4 inhibitor, so an increase in isavuconazole exposure is not expected. No clinically significant interaction is established.
How serious is the interaction between Isavuconazonium and Propofol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is needed; use routine monitoring.
What other medicines interact with Propofol?
MediHelp also lists interactions of Propofol with, for example, Alfentanil, Alprazolam, Amobarbital. The full list is on the Propofol page.
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