Drug interactions
Lacosamide + Tipranavir
Severity: Minor
Lacosamide and Tipranavir: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tipranavir with ritonavir has complex effects on CYP3A4, mostly net inhibition. Lacosamide exposure may change modestly, but lacosamide's multiple clearance routes limit the clinical impact.
What this interaction means in plain words
Lacosamide and Tipranavir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Lacosamide belongs to Central Nervous System; Tipranavir belongs to Anti Virals.
Why it happens
Net CYP3A4 modulation by ritonavir-boosted tipranavir may alter a minor lacosamide metabolic pathway.
What to do
No empirical dose change is needed; monitor tolerability and seizure control and adjust lacosamide as required.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Lacosamide
- Lacosamide + Zuranolone Major
- Atazanavir + Lacosamide Moderate
- Carbamazepine + Lacosamide Moderate
- Cenobamate + Lacosamide Moderate
- Clarithromycin + Lacosamide Moderate
- Daridorexant + Lacosamide Moderate
Other interactions of Tipranavir
- Alfuzosin + Tipranavir Contraindicated
- Amiodarone + Tipranavir Contraindicated
- Atorvastatin + Tipranavir Contraindicated
- Avanafil + Tipranavir Contraindicated
- Cisapride + Tipranavir Contraindicated
- Colchicine + Tipranavir Contraindicated
Frequently asked questions
Can I take Lacosamide with Tipranavir?
MediHelp rates the interaction as minor. Lacosamide and Tipranavir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tipranavir with ritonavir has complex effects on CYP3A4, mostly net inhibition. Lacosamide exposure may change modestly, but lacosamide's multiple clearance routes limit the clinical impact.
How serious is the interaction between Lacosamide and Tipranavir?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No empirical dose change is needed; monitor tolerability and seizure control and adjust lacosamide as required.
What other medicines interact with Lacosamide?
MediHelp also lists interactions of Lacosamide with, for example, Zuranolone, Atazanavir, Carbamazepine. The full list is on the Lacosamide page.
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