Drug interactions
Lanthanum carbonate + Magnesium
Severity: Moderate
Lanthanum carbonate and Magnesium: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Magnesium-containing antacids can bind lanthanum or interfere with its dissociation and phosphate binding in the gut. This may reduce lanthanum's effectiveness and the absorption of magnesium. Phosphate control may be less reliable if both are taken together.
What this interaction means in plain words
Lanthanum carbonate and Magnesium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Lanthanum carbonate belongs to Miscellaneous; Magnesium belongs to Gastrointestinal Tract.
Why it happens
Chelation or binding between polyvalent cations and lanthanum in the gastrointestinal tract reduces absorption and the efficacy of one or both agents.
What to do
Separate administration of magnesium-containing antacids and lanthanum carbonate by at least 2 hours. Monitor serum phosphate to confirm control.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Lanthanum carbonate
Other interactions of Magnesium
- Ciprofloxacin + Magnesium Major
- Magnesium + Pancuronium Major
- Magnesium + Rocuronium Major
- Magnesium + Vecuronium Major
- Amikacin + Magnesium Moderate
- Amphotericin b deoxycholate + Magnesium Moderate
Frequently asked questions
Can I take Lanthanum carbonate with Magnesium?
MediHelp rates the interaction as moderate. Lanthanum carbonate and Magnesium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Magnesium-containing antacids can bind lanthanum or interfere with its dissociation and phosphate binding in the gut. This may reduce lanthanum's effectiveness and the absorption of magnesium. Phosphate control may be less reliable if both are taken together.
How serious is the interaction between Lanthanum carbonate and Magnesium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate administration of magnesium-containing antacids and lanthanum carbonate by at least 2 hours. Monitor serum phosphate to confirm control.
What other medicines interact with Lanthanum carbonate?
MediHelp also lists interactions of Lanthanum carbonate with, for example, Aluminum hydroxide, Calcium carbonate, Chloroquine. The full list is on the Lanthanum carbonate page.
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