Drug interactions
Lanthanum carbonate + Simvastatin
Severity: Minor
Lanthanum carbonate and Simvastatin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lanthanum may bind to simvastatin in the gut and reduce its absorption. This could modestly diminish the cholesterol-lowering effect.
What this interaction means in plain words
Lanthanum carbonate and Simvastatin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Lanthanum carbonate belongs to Miscellaneous; Simvastatin belongs to Cardiovascular.
Why it happens
Lanthanum cations bind statin in the GI tract, reducing absorption.
What to do
Give simvastatin at least 2 hours before or after lanthanum carbonate.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Simvastatin
- Atazanavir + Simvastatin Contraindicated
- Clarithromycin + Simvastatin Contraindicated
- Cobicistat + Simvastatin Contraindicated
- Cyclosporine + Simvastatin Contraindicated
- Cyclosporin + Simvastatin Contraindicated
- Danazol + Simvastatin Contraindicated
Other interactions of Lanthanum carbonate
Frequently asked questions
Can I take Lanthanum carbonate with Simvastatin?
MediHelp rates the interaction as minor. Lanthanum carbonate and Simvastatin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Lanthanum may bind to simvastatin in the gut and reduce its absorption. This could modestly diminish the cholesterol-lowering effect.
How serious is the interaction between Lanthanum carbonate and Simvastatin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give simvastatin at least 2 hours before or after lanthanum carbonate.
What other medicines interact with Simvastatin?
MediHelp also lists interactions of Simvastatin with, for example, Atazanavir, Clarithromycin, Cobicistat. The full list is on the Simvastatin page.
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