Drug interactions
Letermovir + Mometasone
Severity: Minor
Letermovir and Mometasone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Letermovir is a moderate CYP3A4 inhibitor and may modestly raise mometasone exposure. The clinical effect is probably small with inhaled or intranasal use but could matter with prolonged high doses.
What this interaction means in plain words
Letermovir and Mometasone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Letermovir belongs to Anti Virals; Mometasone belongs to Respiratory.
Why it happens
Letermovir inhibits CYP3A4, modestly reducing mometasone clearance.
What to do
Monitor for signs of corticosteroid excess with prolonged use and reduce the mometasone dose if they appear.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Mometasone
- Mometasone + Ritonavir Major
- Atazanavir + Mometasone Moderate
- Clarithromycin + Mometasone Moderate
- Cobicistat + Mometasone Moderate
- Darunavir + Mometasone Moderate
- Elvitegravir / cobicistat / emtricitabine / tenofovir df + Mometasone Moderate
Other interactions of Letermovir
- Ergotamine + Letermovir Contraindicated
- Letermovir + Pimozide Contraindicated
- Apalutamide + Letermovir Major
- Atorvastatin + Letermovir Major
- Carbamazepine + Letermovir Major
- Colchicine + Letermovir Major
Frequently asked questions
Can I take Letermovir with Mometasone?
MediHelp rates the interaction as minor. Letermovir and Mometasone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Letermovir is a moderate CYP3A4 inhibitor and may modestly raise mometasone exposure. The clinical effect is probably small with inhaled or intranasal use but could matter with prolonged high doses.
How serious is the interaction between Letermovir and Mometasone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for signs of corticosteroid excess with prolonged use and reduce the mometasone dose if they appear.
What other medicines interact with Mometasone?
MediHelp also lists interactions of Mometasone with, for example, Ritonavir, Atazanavir, Clarithromycin. The full list is on the Mometasone page.
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