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Drug interactions

Levocetirizine + Metoclopramide

Severity: Minor

Levocetirizine and Metoclopramide: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Levocetirizine can cause drowsiness in some patients, which may be additive with metoclopramide's sedative effects. The interaction is generally mild.

What this interaction means in plain words

Levocetirizine and Metoclopramide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Levocetirizine belongs to Respiratory; Metoclopramide belongs to Gastrointestinal Tract.

Evidence level: Low

Why it happens

Mild additive CNS depression.

What to do

Counsel on possible drowsiness and avoid driving if affected. No dose changes are normally needed.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Levocetirizine with Metoclopramide?

MediHelp rates the interaction as minor. Levocetirizine and Metoclopramide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Levocetirizine can cause drowsiness in some patients, which may be additive with metoclopramide's sedative effects. The interaction is generally mild.

How serious is the interaction between Levocetirizine and Metoclopramide?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel on possible drowsiness and avoid driving if affected. No dose changes are normally needed.

What other medicines interact with Metoclopramide?

MediHelp also lists interactions of Metoclopramide with, for example, Amantadine, Amoxapine, Antipsychotics (e.g., haloperidol). The full list is on the Metoclopramide page.

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