Drug interactions
Maraviroc + Prednisone
Severity: Minor
Maraviroc and Prednisone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Prednisone is not a significant CYP3A4 inducer, so no meaningful reduction in maraviroc exposure is expected. Maraviroc has no known effect on corticosteroids. Additive immunosuppression may be a consideration in HIV but is not an interaction.
What this interaction means in plain words
Maraviroc and Prednisone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Maraviroc belongs to Anti Virals; Prednisone belongs to Endocrine.
Why it happens
Maraviroc is a CYP3A4 substrate; prednisone has at most weak induction without proven clinical effect.
What to do
No dose adjustment is required. Monitor viral load per routine HIV care.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Prednisone
- Bcg vaccine live + Prednisone Contraindicated
- Measles vaccine + Prednisone Contraindicated
- Mifepristone + Prednisone Contraindicated
- Prednisone + Radium-223 dichloride Contraindicated
- Prednisone + Smallpox vaccine live Contraindicated
- Adenovirus types 4 and 7 live + Prednisone Major
Other interactions of Maraviroc
- Amobarbital + Maraviroc Major
- Apalutamide + Maraviroc Major
- Carbamazepine + Maraviroc Major
- Clarithromycin + Maraviroc Major
- Efavirenz + Maraviroc Major
- Enzalutamide + Maraviroc Major
Frequently asked questions
Can I take Maraviroc with Prednisone?
MediHelp rates the interaction as minor. Maraviroc and Prednisone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Prednisone is not a significant CYP3A4 inducer, so no meaningful reduction in maraviroc exposure is expected. Maraviroc has no known effect on corticosteroids. Additive immunosuppression may be a consideration in HIV but is not an interaction.
How serious is the interaction between Maraviroc and Prednisone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is required. Monitor viral load per routine HIV care.
What other medicines interact with Prednisone?
MediHelp also lists interactions of Prednisone with, for example, Bcg vaccine live, Measles vaccine, Mifepristone. The full list is on the Prednisone page.
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